Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.57 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1357714 | 1.00 | KMT2A (0.69) | KMT2AADORA1HCRTR2DPP8DPP9 | |
| SCHEMBL1357718 | 1.00 | KMT2A (0.69) | KMT2AADORA1HCRTR2DPP8DPP9 | |
| SCHEMBL6164761 | 0.92 | KMT2A (0.60) | KMT2AADORA1DPP8DPP9HDAC8 | |
| SCHEMBL8244870 | 0.92 | KMT2A (0.60) | KMT2AADORA1DPP8DPP9HDAC8 | |
| SCHEMBL9545302 | 0.90 | KMT2A (0.55) | KMT2AADORA1HCRTR2HDAC8MAPK1 | |
| SCHEMBL6163179 | 0.88 | ADORA1 (0.60) | KMT2AADORA1HCRTR2MAPK1SCN9A | |
| SCHEMBL6163173 | 0.88 | ADORA1 (0.60) | KMT2AADORA1HCRTR2MAPK1SCN9A | |
| SCHEMBL6428456 | 0.88 | HCRTR2 (0.76) | KMT2AADORA1HCRTR2HCRTR1 | |
| SCHEMBL9542529 | 0.85 | CCKBR (0.58) | CTSSCTSKCTSLACE | |
| SCHEMBL13291363 | 0.84 | KMT2A (0.64) | KMT2AADORA1MAPK1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |