SCHEMBL9544270

CC(C)(C)OC(=O)N1c2ccccc2C[C@@H]1C(=O)N1[C@@H](C(=O)N2Cc3ccccc3C[C@@H]2CC(=O)N2CCC[C@H]2C(=O)O)CC[C@H]1c1ccccc1

nearest known ligand 0.83

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	OPRD1	P41143	1/20	0.40

▸	UCHL1	P09936	1/20	0.37

▸	ACE	P12821	1/20	0.37

▸	PREP	P48147	5/20	0.37

▸	CHRM2	P08172	1/20	0.37

▸	CHRM4	P08173	1/20	0.37

▸	CHRM1	P11229	1/20	0.37

▸	CHRM3	P20309	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9545259	1.00	OPRD1 (0.40)	OPRD1UCHL1ACEPREPCHRM2
SCHEMBL9544258	1.00	OPRD1 (0.40)	OPRD1UCHL1ACEPREPCHRM2
SCHEMBL9545273	1.00	OPRD1 (0.40)	OPRD1UCHL1ACEPREPCHRM2
SCHEMBL9544898	1.00	OPRD1 (0.40)	OPRD1UCHL1ACEPREPCHRM2
SCHEMBL9544917	1.00	OPRD1 (0.40)	OPRD1UCHL1ACEPREPCHRM2
SCHEMBL9545352	0.94	OPRD1 (0.40)	OPRD1UCHL1PREP
SCHEMBL9542554	0.94	OPRD1 (0.40)	OPRD1UCHL1PREP
SCHEMBL9545363	0.94	OPRD1 (0.40)	OPRD1UCHL1PREP
SCHEMBL9542538	0.94	OPRD1 (0.40)	OPRD1UCHL1PREP
SCHEMBL9543563	0.91	UCHL1 (0.41)	OPRD1UCHL1PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1993020099-A2	CCK AND/OR GASTRIN RECEPTOR LIGANDS	FERRING B.V. (NL)	1993-10-14	—	—	WO	claimed
WO-1993020099-A2	CCK AND/OR GASTRIN RECEPTOR LIGANDS	FERRING B.V. (NL)	1993-10-14	—	—	WO	disclosed