Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.36 |
| ▸ | ADH1C | P00326 | 2/20 | 0.36 |
| ▸ | ADH1A | P07327 | 2/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1752018 | 0.77 | ADH1B (0.40) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL6292489 | 0.74 | ADH1B (0.30) | ADH1BADH1CADH1A | |
| SCHEMBL7529599 | 0.73 | ADH1B (0.37) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL8449534 | 0.73 | ADH1B (0.35) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL7523004 | 0.66 | — | — | |
| SCHEMBL11873574 | 0.66 | — | — | |
| SCHEMBL7767539 | 0.64 | ADH1B (0.31) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL11280040 | 0.64 | ADH1B (0.37) | ADH1BADH1CADH1A | |
| SCHEMBL5383423 | 0.64 | — | — | |
| SCHEMBL5113370 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018002-A1 | QUATERNARY SALTS OF 4-SUBSTITUTED PIPERIDINES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ELF SANOFI (FR) | 1993-09-16 | — | — | WO | disclosed |
| EP-0559538-A1 | Quaternary salts of 4-substituted piperidines, their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1993-09-08 | — | — | EP | disclosed |