SCHEMBL11280040

SCHEMBL11280040

[CH2]CC(NC=O)OCC(C)C

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 2/20 0.37
ADH1C P00326 2/20 0.37
ADH1A P07327 2/20 0.37
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8453040 0.79 ADH1B (0.39) ADH1BADH1CADH1ATSHR
SCHEMBL11873574 0.74
SCHEMBL11081449 0.69 ADH1B (0.32) ADH1BADH1CADH1A
SCHEMBL2987089 0.68 TSHR (0.34) ADH1BADH1CADH1ATSHR
SCHEMBL3824259 0.66 EPHX1 (0.47) ADH1BADH1CADH1ATSHR
SCHEMBL9544388 0.64 ADH1B (0.36) ADH1BADH1CADH1A
SCHEMBL19189 0.63
SCHEMBL10725876 0.63
SCHEMBL7670411 0.61
SCHEMBL10572954 0.61 ALDH1A1 (0.36) ADH1BADH1CADH1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0055562-A2 Cephalosporin derivatives ICI PHARMA (FR) 1982-07-07 EP claimed
EP-0055562-A2 Cephalosporin derivatives ICI PHARMA (FR) 1982-07-07 EP disclosed