Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 7/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541777 | 0.92 | MGLL (0.47) | MGLLNPC1RAB9AACHE | |
| SCHEMBL9541840 | 0.92 | NPC1 (0.54) | MGLLNPC1RAB9A | |
| SCHEMBL9543483 | 0.92 | NPC1 (0.54) | MGLLNPC1RAB9A | |
| SCHEMBL9682837 | 0.92 | NPC1 (0.54) | MGLLNPC1RAB9A | |
| SCHEMBL9681832 | 0.92 | NPC1 (0.54) | MGLLNPC1RAB9A | |
| SCHEMBL9542179 | 0.92 | NPC1 (0.54) | MGLLNPC1RAB9A | |
| SCHEMBL9541815 | 0.88 | NPC1 (0.56) | NPC1RAB9A | |
| SCHEMBL9233369 | 0.87 | NPC1 (0.48) | MGLLNPC1RAB9AACHE | |
| SCHEMBL8707756 | 0.87 | NPC1 (0.48) | MGLLNPC1RAB9AACHE | |
| SCHEMBL8952484 | 0.83 | MGLL (0.46) | MGLLACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013067-A1 | 4-SUBSTITUTED PIPERIDINECARBOXYLIC ACID ESTERS: INHIBITION OF CHOLESTEROL ABSORPTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-07-08 | — | — | WO | claimed |
| US-5169844-A | Enzyme inhibitor, anticholesterol and antilipemic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-12-08 | — | — | US | claimed |
| US-5169844-A | Enzyme inhibitor, anticholesterol and antilipemic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |