Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682837 | 1.00 | NPC1 (0.54) | NPC1RAB9AGAAZDHHC2MGLL | |
| SCHEMBL9542179 | 1.00 | NPC1 (0.54) | NPC1RAB9AGAAZDHHC2MGLL | |
| SCHEMBL9543483 | 1.00 | NPC1 (0.54) | NPC1RAB9AGAAZDHHC2MGLL | |
| SCHEMBL9541840 | 1.00 | NPC1 (0.54) | NPC1RAB9AGAAZDHHC2MGLL | |
| SCHEMBL9541815 | 0.96 | NPC1 (0.56) | NPC1RAB9AGAACHRM3 | |
| SCHEMBL8707756 | 0.94 | NPC1 (0.48) | NPC1RAB9AGAAZDHHC2MGLL | |
| SCHEMBL9233369 | 0.94 | NPC1 (0.48) | NPC1RAB9AGAAZDHHC2MGLL | |
| SCHEMBL9541777 | 0.92 | MGLL (0.47) | NPC1RAB9AMGLL | |
| SCHEMBL9544580 | 0.92 | MGLL (0.46) | NPC1RAB9AMGLL | |
| SCHEMBL8488443 | 0.91 | NPC1 (0.55) | NPC1RAB9AGAAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169844-A | Enzyme inhibitor, anticholesterol and antilipemic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-12-08 | — | — | US | claimed |
| US-5169844-A | Enzyme inhibitor, anticholesterol and antilipemic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |