Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 3/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544665 | 0.83 | MAPT (0.46) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL8128147 | 0.83 | PTGS1 (0.45) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| Methoxymethane SCHEMBL11481514 | 0.82 | PPARG (0.49) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL30089557 | 0.81 | PTGS1 (0.53) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL26555579 | 0.81 | CXCR1 (0.50) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL9362203 | 0.80 | SLC7A5 (0.56) | PTGS1PTGS2LMNANFKB1HTR2A | |
| SCHEMBL2140146 | 0.79 | PTGS1 (0.52) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL5458217 | 0.79 | RAB9A (0.56) | LMNANFKB1MEN1ALDH1A1HPGD | |
| SCHEMBL9441164 | 0.79 | PTGS1 (0.52) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL5460100 | 0.79 | NPC1 (0.45) | LMNAMEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016996-A1 | INDOLE DERIVATIVES AS TESTOSTERONE-5-ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-02 | — | — | WO | disclosed |