Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxymethane SCHEMBL11481514 | 0.94 | PPARG (0.49) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| Ether SCHEMBL11548898 | 0.88 | PPARG (0.45) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL30089557 | 0.86 | PTGS1 (0.53) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL8083048 | 0.85 | HSD17B3 (0.58) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL7716957 | 0.85 | MAPT (0.47) | CYP2C9SMN1; SMN2MAPTL3MBTL1PPARG | |
| SCHEMBL9441164 | 0.84 | PTGS1 (0.52) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL9543302 | 0.82 | FAAH (0.59) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL4818283 | 0.82 | GSK3B (0.57) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL8959879 | 0.82 | HSD17B3 (0.61) | L3MBTL1 | |
| SCHEMBL21064585 | 0.81 | PTGS1 (0.57) | PTGS1PTGS2LMNACYP2C9AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229165-A1 | A SYNERGISTIC PERFUMING COMPOSITION | Firmenich SA (CH) | 2023-08-23 | — | — | EP | claimed |
| CN-112853384-B | Method for synthesizing ibuprofen intermediate by taking halogen ions as electrocatalyst | 北京工业大学 | 2022-07-12 | — | — | CN | claimed |
| WO-2022129351-A1 | A SYNERGISTIC PERFUMING COMPOSITION | FIRMENICH SA (CH) | 2022-06-23 | — | — | WO | claimed |
| CN-112853384-A | Method for synthesizing ibuprofen intermediate by taking halogen ions as electrocatalyst | 北京工业大学 | 2021-05-28 | — | — | CN | claimed |
| CN-107793354-A | A kind of method of intermolecular cyclization synthesis of quinoline derivatives | 沅江华龙催化科技有限公司 | 2018-03-13 | — | — | CN | claimed |
| US-8426630-B2 | Method and apparatus for continuous flow synthesis of ibuprofen | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-04-23 | — | — | US | claimed |
| US-20110054208-A1 | METHOD AND APPARATUS FOR CONTINUOUS FLOW SYNTHESIS OF IBUPROFEN | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-03-03 | — | — | US | claimed |
| CN-101456808-A | Method for preparing ibuprofen | UNIV CHANGSHA SCIENCE (CN) | 2009-06-17 | — | — | CN | claimed |
| US-5221766-A | Oxidizing 2-/p-isobutylphenyl/propionaldehyde at low reaction temperature in presence of inorganic acid using hypohalogenite | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1993-06-22 | — | — | US | claimed |
| US-4843169-A | REACTING A TRIVALENT IODINE COMPOUND WITH CARBONYL COMPOUND IN PRESENCE OF ORTHOCARBOXYLIC ESTER AND SULFURIC ACID | MALLINCKRODT, INC. (US) | 1989-06-27 | — | — | US | claimed |
| US-4730077-A | TRIVALENT IODINE COMPOUND, AROMATIC KETONE, ORTHO ESTER, ANHYDROUS | MALLINCKRODT, INC. (US) | 1988-03-08 | — | — | US | claimed |
| US-4142054-A | TRIVALENT THALLIUM SALT | THE UPJOHN COMPANY (US) | 1979-02-27 | — | — | US | claimed |
| CN-121913890-A | Method and device for acylation of isobutyl benzene | 中国石油化工股份有限公司 | 2026-04-24 | — | — | CN | disclosed |
| US-12018226-B2 | Perfuming compositions | FIRMENICH SA (CH) | 2024-06-25 | — | — | US | disclosed |
| CN-117362165-A | Preparation method of ibuprofen | 山东新华制药股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-112853384-B | Method for synthesizing ibuprofen intermediate by taking halogen ions as electrocatalyst | 北京工业大学 | 2022-07-12 | — | — | CN | disclosed |
| US-4198510-A | INTERMEDIATES FOR AROMATIC-SUBSTITUTED CARBOXYLIC ACIDS | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1980-04-15 | — | — | US | disclosed |
| US-4143229-A | PROCESS FOR THE PREPARATION OF PARA-SUBSTITUTED DERIVATIVES OF ALPHA-PHENYLPROPIONIC ACID | ALCAR S.R.L. (IT) | 1979-03-06 | — | — | US | disclosed |
| US-4142054-A | TRIVALENT THALLIUM SALT | THE UPJOHN COMPANY (US) | 1979-02-27 | — | — | US | disclosed |
| US-4135051-A | ENOL ETHER OF AN ARYL ALKYL KETONE WITH A THALLIJM SALT, REGENERATION OF THALLIUM SALT BY ADDING PERACID AND REACTIVE METAL COMPOUND | THE UPJOHN COMPANY (US) | 1979-01-16 | — | — | US | disclosed |