Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380954 | 0.82 | CNR1 (0.50) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL9544860 | 0.82 | FFAR1 (0.41) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL6556166 | 0.81 | CNR1 (0.42) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL21633649 | 0.79 | LPL (0.45) | CNR1CNR2LPLLIPG | |
| SCHEMBL7648656 | 0.78 | LPL (0.44) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL2920784 | 0.77 | GRIN2D (0.42) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL31455995 | 0.76 | TP53 (0.48) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL589019 | 0.76 | TP53 (0.48) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL5424543 | 0.76 | MTNR1A (0.47) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL5252816 | 0.76 | LPL (0.47) | CNR1CNR2LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013089-A1 | MACROCYCLIC POLYETHER CARBOXYLIC ACIDS | URBAN FRANK J (US) | 1993-07-08 | — | — | WO | disclosed |