Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041118 | 0.82 | KDM4E (0.50) | KDM4ETDP1DAOPARP1PADI4 | |
| SCHEMBL31171910 | 0.77 | EIF4A3 (0.43) | KDM4ETDP1DAOEGLN1GPR84 | |
| SCHEMBL15546942 | 0.77 | PKM (0.39) | KDM4EDAOEGLN1GPR84THRB | |
| SCHEMBL476755 | 0.71 | KDM4E (0.72) | KDM4ETDP1DAOPARP1GPR35 | |
| SCHEMBL30388663 | 0.71 | KDM4E (0.72) | KDM4ETDP1DAOPARP1GPR35 | |
| SCHEMBL9389006 | 0.70 | DAO (0.54) | DAO | |
| SCHEMBL31146049 | 0.70 | PTGS2 (0.36) | DAOPARP1GRIK1LMNAHPGD | |
| SCHEMBL31145935 | 0.70 | PTGS2 (0.36) | DAOPARP1GRIK1LMNAHPGD | |
| SCHEMBL31145855 | 0.70 | PIM1 (0.44) | KDM4EALDH1A1CYP2C19 | |
| SCHEMBL27353990 | 0.70 | HDAC3 (0.39) | DAOGPR84ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5092922-A | — | — | None | — | — | JP | disclosed |
| JP-H0592922-A | ANTIBACTERIAL AGENT | BAYER AG | 1993-04-16 | — | — | JP | disclosed |
| US-4952695-A | Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid, intermediate for antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1990-08-28 | — | — | US | disclosed |
| US-4556658-A | 7-Amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acids and antibacterial agents containing these compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-03 | — | — | US | disclosed |
| JP-H00592922-A | — | — | 0001-01-01 | — | — | JP | disclosed |