Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | PTGFR | P43088 | 4/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.59 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.59 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.59 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.48 |
| ▸ | PTGIR | P43119 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thromboxane B2 SCHEMBL13179230 | 0.89 | MEN1 (1.00) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| Thromboxane B2 SCHEMBL22972728 | 0.89 | MEN1 (1.00) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| Thromboxane B2 SCHEMBL38223 | 0.89 | MEN1 (1.00) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| Thromboxane B2 SCHEMBL15263306 | 0.89 | MEN1 (1.00) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| Thromboxane B2 SCHEMBL21820779 | 0.89 | MEN1 (1.00) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL31254102 | 0.81 | MEN1 (0.84) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL38663703 | 0.80 | MEN1 (0.81) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL29559217 | 0.80 | MEN1 (0.81) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL3344355 | 0.80 | MEN1 (0.81) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL13179231 | 0.80 | MEN1 (0.81) | MEN1KMT2APTGFRTBXA2RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009777-A1 | TOCOTRIENOLS AND TOCOTRIENOL-LIKE COMPOUNDS AND METHODS FOR THEIR USE | LIPOGENICS, INC. (US) | 1993-05-27 | — | — | WO | disclosed |