Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 10/20 | 0.51 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.51 |
| ▸ | IL1RN | P18510 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | NPY4R | P50391 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 4/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545184 | 1.00 | BACE1 (0.51) | BACE1BACE2IL1RNERAP2NPY1R | |
| SCHEMBL30895730 | 0.86 | ACE (0.65) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL30343610 | 0.86 | NAALAD2 (0.54) | BACE1BACE2IL1RNERAP2NPY1R | |
| SCHEMBL31284997 | 0.86 | IL1RN (0.55) | BACE1BACE2IL1RNERAP2NPY1R | |
| SCHEMBL30643194 | 0.85 | BACE1 (0.56) | BACE1BACE2IL1RNERAP2NPY1R | |
| SCHEMBL30512536 | 0.84 | BACE1 (0.56) | BACE1BACE2CTSD | |
| SCHEMBL30449184 | 0.84 | ACE (0.58) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL30973981 | 0.84 | NPY4R (0.56) | BACE1BACE2IL1RNERAP2NPY1R | |
| SCHEMBL30713460 | 0.84 | OPRD1 (0.51) | IL1RNERAP2NPY1RNPY2RNPY4R | |
| SCHEMBL31134397 | 0.83 | ENPEP (0.55) | BACE1BACE2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021206-A1 | SYNTHETIC, STABILIZED, THREE-DIMENSION POLYPEPTIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-10-28 | — | — | WO | claimed |