SCHEMBL9117736

SCHEMBL9117736

CCCCCCCCCCCCSC[C@H](NC(C)=O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ICMT O60725 1/20 0.53
MAPT P10636 3/20 0.51
CES2 O00748 3/20 0.51
THRB P10828 2/20 0.51
BLM P54132 2/20 0.51
GMNN O75496 1/20 0.51
TP53 P04637 1/20 0.51
POLB P06746 1/20 0.51
CYP2C9 P11712 1/20 0.51
HSD17B10 Q99714 1/20 0.51
NOD1 Q9Y239 1/20 0.45
ALDH1A1 P00352 2/20 0.45
KDM4E B2RXH2 1/20 0.44
ALOX15 P16050 1/20 0.44
NFKB1 P19838 1/20 0.44
PTGS2 P35354 1/20 0.44
THPO P40225 1/20 0.44
RECQL P46063 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
FAAH O00519 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9545188 1.00 ICMT (0.53) ICMTMAPTCES2THRBBLM
SCHEMBL9545182 1.00 ICMT (0.53) ICMTMAPTCES2THRBBLM
SCHEMBL9119016 1.00 ICMT (0.53) ICMTMAPTCES2THRBBLM
SCHEMBL19927710 1.00 ICMT (0.53) ICMTMAPTCES2THRBBLM
SCHEMBL19927712 1.00 ICMT (0.53) ICMTMAPTCES2THRBBLM
SCHEMBL4953347 0.93 ICMT (0.49) ICMTMAPTCES2THRBBLM
SCHEMBL23117309 0.92 ICMT (0.50) ICMTMAPTCES2THRBBLM
SCHEMBL9275572 0.92 ICMT (0.50) ICMTMAPTCES2THRBBLM
SCHEMBL23117307 0.92 ICMT (0.50) ICMTMAPTCES2THRBBLM
SCHEMBL9275581 0.92 ICMT (0.50) ICMTMAPTCES2THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995034303-A1 METHOD FOR THE TREATMENT, PREVENTION OR MINIMIZATION OF HAIR LOSS ARCTURUS PHARMACEUTICAL CORPORATION (US) 1995-12-21 WO claimed
WO-1995000136-A1 METHOD FOR TREATING HYPERKERATOSIS AND DISEASES MEDIATED BY PROTEASES ARCTURUS PHARMACEUTICAL CORPORATION (US) 1995-01-05 WO claimed
US-20210087337-A1 COMPOUNDS, COMPOSITIONS AND METHODS RELATED TO ANTIMICROBIAL APPLICATIONS VYOME THERAPEUTICS LIMITED (IN) 2021-03-25 US disclosed
US-20200140460-A1 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS VYOME BIOSCIENCES PVT. LTD. (IN) 2020-05-07 US disclosed
US-10570152-B2 Antibacterial therapeutics and prophylactics VYOME THERAPEUTICS LIMITED (IN) 2020-02-25 US disclosed
EP-3507325-A2 COMPOUNDS, COMPOSITONS AND METHODS RELATED TO ANTIMICROBIAL APPLICATIONS Vyome Therapeutics Limited (IN) 2019-07-10 EP disclosed
US-20180265523-A1 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS VYOME THERAPEUTICS LIMITED (IN) 2018-09-20 US disclosed
EP-3328856-A2 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS Vyome Biosciences Pvt. Ltd. (IN) 2018-06-06 EP disclosed
WO-2018042367-A2 COMPOUNDS, COMPOSITONS AND METHODS RELATED TO ANTIMICROBIAL APPLICATIONS VYOME BIOSCIENCES PVT. LTD. (IN) 2018-03-08 WO disclosed
WO-2017017631-A2 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS VYOME BIOSCIENCES PVT. LTD. (IN) 2017-02-02 WO disclosed
WO-1995034303-A1 METHOD FOR THE TREATMENT, PREVENTION OR MINIMIZATION OF HAIR LOSS ARCTURUS PHARMACEUTICAL CORPORATION (US) 1995-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180265523-A1 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS CLPP, CFTR, ELANE ICMT 1794/4885MAPT 3826/4885CES2 3133/4885
US-20200140460-A1 ANTIBACTERIAL THERAPEUTICS AND PROPHYLACTICS CLPP, CFTR, ELANE ICMT 1794/4885MAPT 3826/4885CES2 3133/4885
US-10570152-B2 Antibacterial therapeutics and prophylactics CLPP, CFTR, ELANE ICMT 1794/4885MAPT 3826/4885CES2 3133/4885
US-20210087337-A1 COMPOUNDS, COMPOSITIONS AND METHODS RELATED TO ANTIMICROBIAL APPLICATIONS CUTA, GMPS, MMP8 ICMT 1810/4885MAPT 3659/4885CES2 2690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.