Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947851 | 0.80 | OPRM1 (0.39) | HTR2ASIGMAR1OPRM1GAASMN1; SMN2 | |
| SCHEMBL10020773 | 0.72 | DPP4 (0.32) | HTR2ASLC6A2SLC6A3 | |
| SCHEMBL10000497 | 0.72 | — | — | |
| SCHEMBL10771537 | 0.71 | HTR2C (0.36) | HTR2ASIGMAR1MEN1CYP3A4CYP2D6 | |
| SCHEMBL10000498 | 0.70 | CHRM2 (0.32) | SIGMAR1CYP2C19CHRM2CHRM1CHRM3 | |
| SCHEMBL10626406 | 0.69 | HTR2A (0.33) | HTR2ASIGMAR1OPRM1 | |
| SCHEMBL3421953 | 0.67 | ITGB2 (0.35) | KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL2758096 | 0.66 | KCNA3 (0.40) | SIGMAR1RAB9A | |
| SCHEMBL20373223 | 0.66 | — | — | |
| SCHEMBL10770562 | 0.64 | PGR (0.33) | MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993017998-A1 | A PROCESS FOR MAKING 2-AMINO-3-METHYL-1-NAPHTHALENECARBONITRILE | THE DOW CHEMICAL COMPANY (US) | 1993-09-16 | — | — | WO | claimed |