Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | POLR1A | O95602 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049947 | 0.86 | KDM4E (0.53) | ALDH1A1KDM4EMAPTCASP1CASP7 | |
| SCHEMBL4720648 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTCASP1CASP7 | |
| SCHEMBL10902462 | 0.85 | HPGD (0.66) | ALDH1A1KDM4EMAPTCASP1CASP7 | |
| SCHEMBL8045020 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTCASP1CASP7 | |
| SCHEMBL4722989 | 0.84 | KDM4E (0.50) | ALDH1A1KDM4EMAPTCASP1CASP7 | |
| SCHEMBL8045771 | 0.83 | KDM4E (0.56) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL4718854 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTCASP1CASP7 | |
| SCHEMBL3296572 | 0.80 | GAA (0.66) | ALDH1A1KDM4EMAPTGAAMEN1 | |
| SCHEMBL8894839 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTCASP1CASP7 | |
| SCHEMBL30226304 | 0.79 | KDM4E (0.51) | ALDH1A1KDM4EMAPTCASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021163-A1 | QUINAZOLONES HAVING CARDIOVASCULAR ACTIVITY | ITALFARMACO S.P.A. (IT) | 1993-10-28 | — | — | WO | disclosed |