Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31187382 | 0.89 | AOX1 (0.46) | KDM4EALDH1A1GAAKDRAURKA | |
| SCHEMBL31187366 | 0.87 | RXFP1 (0.44) | KDM4EALDH1A1GAAKDRAURKA | |
| SCHEMBL31187364 | 0.86 | MTNR1A (0.60) | KDRAURKALCKMETTEK | |
| SCHEMBL8045020 | 0.85 | ALDH1A1 (0.57) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL2117675 | 0.85 | PLK1 (0.66) | ALDH1A1KMT2AMEN1PLK1BRD4 | |
| SCHEMBL4718854 | 0.84 | ALDH1A1 (0.56) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL30226304 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1GAAKDRAURKA | |
| SCHEMBL163431 | 0.83 | KMT2A (0.46) | KDM4EALDH1A1GAAKDRAURKA | |
| SCHEMBL9545429 | 0.83 | ALDH1A1 (0.63) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL4723210 | 0.81 | PLK1 (0.71) | KDM4EALDH1A1GAAKDRAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789020-B1 | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL CO (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5780628-A | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0789020-A1 | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-13 | — | — | EP | disclosed |