Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22716785 | 0.80 | CYP1A2 (0.65) | ALDH1A1HPGDKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL31189218 | 0.80 | CYP1A2 (0.65) | ALDH1A1HPGDKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL7655992 | 0.77 | ALDH1A1 (0.70) | ALDH1A1HPGDKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL30089550 | 0.75 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL30581253 | 0.75 | ALDH1A1 (0.69) | ALDH1A1HPGDKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL4199990 | 0.75 | ALDH1A1 (0.69) | ALDH1A1HPGDKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL5878601 | 0.75 | ALDH1A1 (0.82) | ALDH1A1HPGDKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL1662185 | 0.75 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL8074180 | 0.75 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL14692183 | 0.75 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4ECYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021163-A1 | QUINAZOLONES HAVING CARDIOVASCULAR ACTIVITY | ITALFARMACO S.P.A. (IT) | 1993-10-28 | — | — | WO | disclosed |