SCHEMBL95456

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18019596	0.90	NPC1 (0.69)	NPC1RAB9AMEN1POLBKMT2A
	SCHEMBL424293	0.88	HDAC8 (0.64)	SMN1; SMN2HDAC8HDAC6HDAC2GAA
	SCHEMBL95844	0.85	RAB9A (0.81)	NPC1RAB9AMEN1POLBKMT2A
	SCHEMBL94356	0.85	CACNA1B (0.71)	NPC1RAB9AMEN1POLBKMT2A
	SCHEMBL94598	0.85	KMT2A (0.59)	NPC1RAB9AMEN1POLBKMT2A
	SCHEMBL15948317	0.83	CACNA1B (0.73)	NPC1RAB9AMEN1POLBKMT2A
	SCHEMBL16610324	0.83	CACNA1B (0.73)	NPC1RAB9AMEN1POLBKMT2A
	SCHEMBL16610200	0.83	DEGS1 (0.64)	NPC1RAB9AMEN1POLBKMT2A
	SCHEMBL12200275	0.83	RAB9A (0.85)	NPC1RAB9AMEN1POLBKMT2A
	SCHEMBL96002	0.82	HDAC3 (0.73)	NPC1RAB9AMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.