Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | APEX1 | P27695 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.60 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12200275 | 0.92 | RAB9A (0.85) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL15948317 | 0.92 | CACNA1B (0.73) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL16610200 | 0.92 | DEGS1 (0.64) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL16610324 | 0.92 | CACNA1B (0.73) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL95456 | 0.90 | NPC1 (0.58) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL15948133 | 0.90 | POLB (0.81) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL15948139 | 0.87 | TRPV1 (0.76) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL18517842 | 0.87 | RAB9A (0.76) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL11774528 | 0.87 | NPC1 (0.59) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL10155589 | 0.87 | ALDH1A1 (0.62) | NPC1RAB9AMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055430-A1 | SUPRAMOLECULAR ADDITIVES FOR SEMICRYSTALLINE PLASTICS | THE UNIVERSITY OF AKRON | 2023-02-23 | — | — | US | disclosed |
| US-9982117-B2 | Thermoset rubber reinforced by supramolecule building blocks | THE UNIVERSITY OF AKRON (US) | 2018-05-29 | — | — | US | disclosed |
| US-20160237261-A1 | THERMOSET RUBBER REINFORCED BY SUPRAMOLECULE BUILDING BLOCKS | THE UNIVERSITY OF AKRON | 2016-08-18 | — | — | US | disclosed |