Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16838833 | 0.80 | APP (0.56) | TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL29304401 | 0.78 | MAOB (0.43) | TAAR1MAPTKMT2A | |
| SCHEMBL4254058 | 0.77 | CALM1 (0.72) | TDP1L3MBTL1CALM1IGF1RALOX15 | |
| SCHEMBL29304013 | 0.77 | MAPT (0.39) | MAPTKMT2A | |
| SCHEMBL10736559 | 0.76 | MAPT (0.60) | KDM4EHPGDMAPTKMT2A | |
| SCHEMBL7943083 | 0.76 | MAPT (0.49) | KDM4EHPGDMAPTKMT2A | |
| SCHEMBL20386693 | 0.76 | LMNA (0.49) | CALM1CASP3SENP8SENP7SENP6 | |
| SCHEMBL13313172 | 0.76 | CALM1 (0.60) | TDP1L3MBTL1CALM1IGF1RALOX15 | |
| SCHEMBL31411878 | 0.76 | TDP1 (0.70) | TDP1L3MBTL1CALM1IGF1RALOX15 | |
| SCHEMBL3335244 | 0.76 | MAPT (0.64) | KDM4EHPGDRAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993022285-A1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-11-11 | — | — | WO | disclosed |