Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9290105 | 0.77 | CNR2 (0.45) | PIN1TSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL8893037 | 0.76 | ESR1 (0.50) | PIN1TSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL841159 | 0.74 | NPSR1 (0.49) | PIN1TSHRHTTLMNAPOLB | |
| SCHEMBL6812442 | 0.74 | TSHR (0.59) | PIN1TSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL18053924 | 0.74 | CYP1A2 (0.51) | PIN1TSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL23291809 | 0.74 | ALDH1A1 (0.48) | PIN1TSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL5807773 | 0.74 | PIN1 (0.57) | PIN1TSHRMMP8POLBNPSR1 | |
| SCHEMBL13574069 | 0.74 | PIN1 (0.57) | PIN1TSHRMMP8POLBNPSR1 | |
| SCHEMBL7986974 | 0.72 | PIN1 (0.51) | PIN1TSHRCYP1A2MMP8LMNA | |
| SCHEMBL11846806 | 0.72 | ESR1 (0.46) | PIN1TSHRABCB11CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993022299-A1 | FUNGICIDAL OXAZOLIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |