Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.44 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137272 | 1.00 | MDM4 (0.47) | MDM4TP53CASP3MDM2SLC17A5 | |
| SCHEMBL9137271 | 1.00 | MDM4 (0.47) | MDM4TP53CASP3MDM2SLC17A5 | |
| SCHEMBL9545902 | 0.90 | MDM4 (0.47) | MDM4TP53CASP3MDM2 | |
| SCHEMBL9136617 | 0.90 | MDM4 (0.47) | MDM4TP53CASP3MDM2 | |
| SCHEMBL9136620 | 0.90 | MDM4 (0.47) | MDM4TP53CASP3MDM2 | |
| SCHEMBL12322470 | 0.90 | MDM4 (0.49) | MDM4TP53CASP3MDM2 | |
| SCHEMBL7868739 | 0.86 | MDM4 (0.49) | MDM4TP53CASP3MDM2SLC17A5 | |
| SCHEMBL9545907 | 0.86 | MDM4 (0.49) | MDM4TP53CASP3MDM2SLC17A5 | |
| SCHEMBL9164727 | 0.86 | MDM4 (0.49) | MDM4TP53CASP3MDM2SLC17A5 | |
| SCHEMBL9136556 | 0.84 | MDM2 (0.49) | MDM4TP53CASP3MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025561-A1 | PHOSPHONOALKYL PHENYLALANINE COMPOUNDS SUITABLY PROTECTED FOR USE IN PEPTIDE SYNTHESIS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-12-23 | — | — | WO | claimed |