Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10337980 | 0.84 | TSHR (0.34) | POLBKMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL4234394 | 0.84 | POLB (0.37) | POLBKMT2AKDM4EMEN1ATM | |
| SCHEMBL5984477 | 0.78 | HTT (0.40) | POLBKMT2AKDM4EHSD17B10MEN1 | |
| SCHEMBL6903843 | 0.76 | POLB (0.36) | POLBHSD17B10ATMMAPTTSHR | |
| SCHEMBL11453583 | 0.74 | HTT (0.41) | POLBKMT2AKDM4EHSD17B10MEN1 | |
| SCHEMBL9331791 | 0.74 | CES2 (0.40) | KMT2AKDM4EMEN1 | |
| SCHEMBL8380021 | 0.74 | CES2 (0.40) | KMT2AKDM4EMEN1 | |
| SCHEMBL19746578 | 0.73 | HTT (0.44) | POLBKMT2AKDM4EHSD17B10MEN1 | |
| SCHEMBL8970777 | 0.73 | MAPT (0.43) | POLBKMT2AKDM4EHSD17B10MEN1 | |
| SCHEMBL10489544 | 0.73 | FABP7 (0.39) | KMT2AMEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025631-A1 | LIQUID CRYSTAL COMPOUNDS, MIXTURES AND DEVICES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1993-12-23 | — | — | WO | disclosed |