SCHEMBL9545948

SCHEMBL9545948

COC(=O)OC1(C(=O)O)C=CC(c2ccccc2)=CC1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
NPC1 O15118 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ATM Q13315 1/20 0.32
FGFR1 P11362 1/20 0.31
SRC P12931 1/20 0.31
FGFR2 P21802 1/20 0.31
FGFR4 P22455 1/20 0.31
FGFR3 P22607 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KMT2A Q03164 2/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10337981 0.86 GAA (0.33) SMN1; SMN2KDM4EKMT2AMEN1
SCHEMBL4234398 0.86 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3NPC1CYP1A2
SCHEMBL5984481 0.81 MEN1 (0.37) SLC6A2SLC6A4SLC6A3NPC1CYP1A2
SCHEMBL29039536 0.80 THRB (0.32)
SCHEMBL6903846 0.79 SMN1; SMN2 (0.32) NPC1CYP1A2CYP2C19RAB9ASMN1; SMN2
SCHEMBL29154634 0.78 GAA (0.33) SMN1; SMN2
SCHEMBL27681208 0.77 FAAH (0.37) SLC6A2SLC6A4CYP2C19RAB9AKMT2A
SCHEMBL8380025 0.77 SOAT1 (0.37) KDM4EKMT2AMEN1
SCHEMBL9331797 0.77 SOAT1 (0.37) KDM4EKMT2AMEN1
SCHEMBL28365819 0.77 NPC1 (0.32) NPC1CYP1A2CYP2C19RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993025631-A1 LIQUID CRYSTAL COMPOUNDS, MIXTURES AND DEVICES THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1993-12-23 WO disclosed