Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29041191 | 0.90 | KMT2A (0.72) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL29041217 | 0.84 | KMT2A (0.84) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL29041235 | 0.83 | KMT2A (0.62) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL29041199 | 0.83 | KMT2A (0.62) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL29041202 | 0.83 | KMT2A (0.62) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL29041233 | 0.83 | L3MBTL1 (0.72) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL6370484 | 0.82 | TSHR (0.55) | KMT2ANPC1MEN1RAB9AMAPT | |
| SCHEMBL29041229 | 0.81 | MAPT (0.65) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL19659999 | 0.80 | L3MBTL1 (0.60) | KMT2AL3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL28326834 | 0.79 | KMT2A (0.64) | KMT2AL3MBTL1NPC1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5051358-A | — | — | None | — | — | JP | disclosed |
| JP-H0551358-A | 3-BENZOYLPROPIONIC ACID DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1993-03-02 | — | — | JP | disclosed |