Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CPA3 | P15088 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775813 | 0.84 | TSHR (0.61) | TSHRKMT2AALDH1A1MAPTLMNA | |
| SCHEMBL9545966 | 0.82 | KMT2A (0.59) | KMT2AALDH1A1MAPTLMNAPOLB | |
| SCHEMBL19642670 | 0.80 | ALDH1A1 (0.62) | TSHRKMT2AALDH1A1MAPTLMNA | |
| SCHEMBL3113026 | 0.79 | KMO (0.63) | TSHRKMT2AALDH1A1MAPTLMNA | |
| Esonarimod SCHEMBL3044466 | 0.78 | KMT2A (0.52) | TSHRKMT2AALDH1A1MAPTLMNA | |
| Esonarimod SCHEMBL18309833 | 0.78 | KMT2A (0.52) | TSHRKMT2AALDH1A1MAPTLMNA | |
| SCHEMBL10782076 | 0.77 | ALDH1A1 (0.58) | TSHRKMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8775647 | 0.77 | ALDH1A1 (0.58) | TSHRKMT2AALDH1A1MAPTLMNA | |
| SCHEMBL28325791 | 0.76 | TSHR (0.56) | TSHRKMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7874903 | 0.76 | KMO (0.68) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050260748-A1 | Adult stem cells and uses thereof | MICHIGAN STATE UNIVERSITY | 2005-11-24 | — | — | US | disclosed |
| WO-2005085422-A1 | ADULT STEM CELLS AND USES THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2005-09-15 | — | — | WO | disclosed |