Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546037 | 0.94 | TSHR (0.42) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL9578307 | 0.94 | TSHR (0.42) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL13414938 | 0.86 | TSHR (0.36) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL9578404 | 0.84 | TSHR (0.35) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL2367786 | 0.83 | TSHR (0.35) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL2367780 | 0.83 | TSHR (0.35) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL3979865 | 0.82 | TSHR (0.38) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL183807 | 0.81 | TSHR (0.42) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL3408391 | 0.81 | TSHR (0.37) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL12636016 | 0.81 | TSHR (0.37) | TSHRUSP2MAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023773-A1 | PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL | CIBA-GEIGY AG (CH) | 1993-11-25 | — | — | WO | disclosed |
| US-5235013-A | Copolymerizing an alkene of 6-10 carbons having one double bond and a side chain methyl group and an acrylic or fluoroacrylic ester | CIBA-GEIGY CORPORATION | 1993-08-10 | — | — | US | disclosed |