Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9578307 | 1.00 | TSHR (0.42) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL9545989 | 0.94 | TSHR (0.35) | TSHRUSP2MAPTCYP1A2CYP2C19 | |
| SCHEMBL9578353 | 0.85 | TSHR (0.42) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL16174485 | 0.84 | USP2 (0.41) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL5889492 | 0.83 | TSHR (0.45) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL24380770 | 0.82 | TSHR (0.44) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL285648 | 0.82 | TSHR (0.44) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL712581 | 0.82 | TSHR (0.44) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL2031372 | 0.82 | TSHR (0.44) | TSHRUSP2MAPTCYP1A2CYP2C9 | |
| SCHEMBL10887440 | 0.82 | TSHR (0.44) | TSHRUSP2MAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023773-A1 | PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL | CIBA-GEIGY AG (CH) | 1993-11-25 | — | — | WO | disclosed |