Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16174485 | 0.94 | USP2 (0.41) | TSHRUSP2MAPT | |
| SCHEMBL2367780 | 0.88 | TSHR (0.35) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL13414938 | 0.84 | TSHR (0.36) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL2368015 | 0.84 | ALOX15 (0.32) | — | |
| SCHEMBL9545989 | 0.83 | TSHR (0.35) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL9578404 | 0.83 | TSHR (0.35) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL2367325 | 0.81 | THRB (0.37) | — | |
| SCHEMBL2367717 | 0.81 | LMNA (0.39) | TSHRMAPTKDM4ETDP1 | |
| SCHEMBL3979865 | 0.81 | TSHR (0.38) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL1681694 | 0.80 | ALOX15 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288496-B2 | Contact lens and its manufacturing method | NIPPON CONTACT LENS INC. (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20110237701-A1 | CONTACT LENS AND ITS MANUFACTURING METHOD | NIPPON CONTACT LENS INC. (JP) | 2011-09-29 | — | — | US | disclosed |
| EP-2369370-A2 | Contact lens and its manufacturing method | Nippon Contact Lens Inc. (JP) | 2011-09-28 | — | — | EP | disclosed |