Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546090 | 0.89 | TSHR (0.39) | TSHRALDH1A1HCAR2ESR1TDP1 | |
| SCHEMBL9747388 | 0.85 | TSHR (0.52) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL28569761 | 0.82 | TSHR (0.49) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL9546128 | 0.81 | ALDH1A1 (0.44) | TSHRALDH1A1NPSR1THRBLMNA | |
| SCHEMBL9748055 | 0.81 | TSHR (0.47) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL3080867 | 0.79 | TSHR (0.53) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL6200579 | 0.79 | TSHR (0.53) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL9745490 | 0.78 | TSHR (0.52) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL7123449 | 0.78 | TSHR (0.52) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL9745135 | 0.78 | TSHR (0.52) | TSHRALDH1A1HPGDATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023773-A1 | PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL | CIBA-GEIGY AG (CH) | 1993-11-25 | — | — | WO | disclosed |
| US-5100762-A | Radiation-sensitive polymer and radiation-sensitive composition containing the same | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |