Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546004 | 0.89 | TSHR (0.49) | TSHRTHRBHCAR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL9546128 | 0.84 | ALDH1A1 (0.44) | TSHRTHRBGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5861520 | 0.78 | TSHR (0.42) | TSHRTHRBHCAR2GAASMN1; SMN2 | |
| SCHEMBL1593009 | 0.78 | TSHR (0.42) | TSHRTHRBHCAR2GAASMN1; SMN2 | |
| SCHEMBL28599285 | 0.77 | HCAR2 (0.39) | TSHRHCAR2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4653225 | 0.76 | TSHR (0.41) | TSHRTHRBHCAR2GAASMN1; SMN2 | |
| SCHEMBL8861755 | 0.76 | TSHR (0.38) | TSHRTHRBHCAR2GAASMN1; SMN2 | |
| SCHEMBL9578332 | 0.75 | TSHR (0.33) | TSHRTHRBGAASMN1; SMN2 | |
| SCHEMBL2818114 | 0.74 | TSHR (0.40) | TSHRTHRBHCAR2GAASMN1; SMN2 | |
| SCHEMBL6657047 | 0.74 | TSHR (0.40) | TSHRTHRBHCAR2GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023773-A1 | PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL | CIBA-GEIGY AG (CH) | 1993-11-25 | — | — | WO | disclosed |