Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546001 | 0.89 | TSHR (0.49) | TSHRTHRBHCAR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL15156752 | 0.86 | TSHR (0.59) | TSHRHCAR2ALDH1A1LMNACES2 | |
| SCHEMBL9546127 | 0.84 | ALDH1A1 (0.44) | TSHRTHRBGAAALDH1A1LMNA | |
| SCHEMBL9546123 | 0.81 | TSHR (0.37) | TSHRTHRBHCAR2GAASMN1; SMN2 | |
| SCHEMBL9546008 | 0.78 | HTT (0.45) | — | |
| SCHEMBL27876308 | 0.78 | TSHR (0.42) | TSHRTHRBHCAR2GAASMN1; SMN2 | |
| SCHEMBL3478021 | 0.77 | TSHR (0.45) | TSHRTHRBHCAR2GAASMN1; SMN2 | |
| SCHEMBL303392 | 0.76 | TSHR (0.41) | TSHRTHRBHCAR2GAASMN1; SMN2 | |
| SCHEMBL4096843 | 0.75 | TSHR (0.44) | TSHRTHRBHCAR2GAASMN1; SMN2 | |
| SCHEMBL2468506 | 0.75 | ALDH1A1 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023773-A1 | PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL | CIBA-GEIGY AG (CH) | 1993-11-25 | — | — | WO | disclosed |
| US-5235013-A | Copolymerizing an alkene of 6-10 carbons having one double bond and a side chain methyl group and an acrylic or fluoroacrylic ester | CIBA-GEIGY CORPORATION | 1993-08-10 | — | — | US | disclosed |
| EP-0478261-A2 | Process for producing oxygen-permeable polymer | CIBA-GEIGY AG (CH) | 1992-04-01 | — | — | EP | disclosed |