SCHEMBL303392

SCHEMBL303392

C=C(C(=O)OCCC)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
THRB P10828 1/20 0.38
CES2 O00748 3/20 0.36
HCAR2 Q8TDS4 1/20 0.35
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
FAAH O00519 8/20 0.33
LMNA P02545 1/20 0.33
CES1 P23141 5/20 0.32
ESR1 P03372 1/20 0.32
CHRM1 P11229 1/20 0.32
SLC6A2 P23975 1/20 0.32
KDR P35968 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL303139 0.89 THRB (0.46) TSHRTHRBCES2ALDH1A1FAAH
SCHEMBL221345 0.88 TSHR (0.52) TSHRCES2HCAR2ALDH1A1FAAH
SCHEMBL4651717 0.86 TSHR (0.59) TSHRCES2HCAR2ALDH1A1FAAH
SCHEMBL27737049 0.85 TSHR (0.62) TSHRCES2HCAR2FAAHCES1
SCHEMBL11938099 0.85 TSHR (0.62) TSHRCES2HCAR2FAAHCES1
SCHEMBL20597710 0.85 TSHR (0.62) TSHRCES2HCAR2FAAHCES1
SCHEMBL27756373 0.85 TSHR (0.62) TSHRCES2HCAR2FAAHCES1
SCHEMBL20598100 0.85 TSHR (0.62) TSHRCES2HCAR2FAAHCES1
SCHEMBL16710938 0.83 TSHR (0.44) TSHRTHRBCES2ALDH1A1TDP1
SCHEMBL304056 0.83 ALDH1A1 (0.47) TSHRTHRBCES2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102585087-B Functional polyacrylic ester HUAIHAI INST TECHNOLOGY 2014-07-02 CN claimed
CN-102634255-A Ocean antifouling paint and preparation method thereof HUAIHAI INST TECHNOLOGY 2012-08-15 CN claimed
CN-102585087-A Functional polyacrylic ester HUAIHAI INST TECHNOLOGY 2012-07-18 CN claimed
US-4613657-A APROTIC SOLVENT ALKALI METAL ALKOXIDE, OPTICS, PAINTS, RESISTS CENTRAL GLASS COMPANY, LIMITED (JP) 1986-09-23 US claimed
EP-4711518-A1 COATED FIBERS AND MOLDED BODY USING SAME Kuraray Co., Ltd. (JP) 2026-03-18 EP disclosed
US-12460111-B2 Reinforcing fibers and production method therefor, and molded article using same KURARAY CO., LTD. (JP) 2025-11-04 US disclosed
WO-2024237206-A1 COATED FIBERS AND MOLDED BODY USING SAME 株式会社クラレ 2024-11-21 WO disclosed
US-11884788-B2 Reinforcing fiber, method for manufacturing same, and molded body using same KURARAY CO., LTD. (JP) 2024-01-30 US disclosed
CN-112204192-B Reinforcing fiber, method for producing same, and molded article using same 株式会社可乐丽 2023-12-01 CN disclosed
US-20230340169-A1 METHOD FOR MANUFACTURING FLUOROPOLYMER DAIKIN INDUSTRIES, LTD. (JP) 2023-10-26 US disclosed
US-20230303808-A1 EMULSION COMPOSITION AND METHOD FOR PRODUCING SAME KURARAY CO., LTD. (JP) 2023-09-28 US disclosed
US-20230303731-A1 METHOD FOR PRODUCING POLYTETRAFLUOROETHYLENE AND COMPOSITION CONTAINING POLYTETRAFLUOROETHYLENE DAIKIN INDUSTRIES, LTD (JP) 2023-09-28 US disclosed
US-7470808-B2 Method for producing fluorine-containing acrylate TOSOH F-TECH, INC. (JP) 2008-12-30 US disclosed
US-20080032241-A1 Resist Polymer, Process For Production Thereof, Resist Composition, And Process For Production Of Substrated With Patterns Thereon MITSUBISHI RAYON CO., LTD. (JP) 2008-02-07 US disclosed
US-20070190449-A1 Resist polymer, resist composition, process for pattern formation, and starting compounds for production of the resist polymer MITSUBISHI RAYON CO., LTD. (JP) 2007-08-16 US disclosed
US-20060127801-A1 Resist polymer and resist composition MITSUBISHI RAYON CO., LTD. (JP) 2006-06-15 US disclosed
US-20060122423-A1 Method for producing fluorine-containing acrylate SAGAMI CHEMICAL RESEARCH CENTER (JP) 2006-06-08 US disclosed
EP-1637514-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING ACRYLATE Tosoh F-Tech, Inc. (JP) 2006-03-22 EP disclosed
US-4613657-A APROTIC SOLVENT ALKALI METAL ALKOXIDE, OPTICS, PAINTS, RESISTS CENTRAL GLASS COMPANY, LIMITED (JP) 1986-09-23 US disclosed
US-4609715-A RADICALLY POLYMERIZED CENTRAL GLASS COMPANY, LIMITED (JP) 1986-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122423-A1 Method for producing fluorine-containing acrylate AFF4, CBR1, AFF1 TSHR 52/4885THRB 917/4885CES2 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.