Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546183 | 1.00 | EPHX2 (0.42) | EPHX2ALOX5OXER1CNR2TYR | |
| SCHEMBL9546354 | 0.88 | PTGER3 (0.43) | TYRABHD16APDE4DPRKCAALDH1A1 | |
| SCHEMBL9546356 | 0.88 | PTGER3 (0.43) | TYRABHD16APDE4DPRKCAALDH1A1 | |
| SCHEMBL9546156 | 0.88 | PPARG (0.48) | OXER1ALDH1A1 | |
| SCHEMBL9734666 | 0.86 | ALOX5 (0.45) | EPHX2ALOX5OXER1CNR2PDE4D | |
| SCHEMBL10607035 | 0.85 | EPHX2 (0.44) | EPHX2ALOX5OXER1CNR2ABHD16A | |
| SCHEMBL10607071 | 0.85 | EPHX2 (0.44) | EPHX2ALOX5OXER1CNR2ABHD16A | |
| SCHEMBL10607027 | 0.85 | EPHX2 (0.44) | EPHX2ALOX5OXER1CNR2ABHD16A | |
| SCHEMBL10603261 | 0.85 | EPHX2 (0.44) | EPHX2ALOX5OXER1CNR2ABHD16A | |
| SCHEMBL10603886 | 0.85 | EPHX2 (0.44) | EPHX2ALOX5OXER1CNR2ABHD16A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332847-B1 | COMPOSITION FOR PREVENTING GRAYING OF THE HAIR AND RESTORING GRAYED HAIR TO ITS NATURAL COLOR | LION CORPORATION (JP) | 1993-07-28 | — | — | EP | claimed |
| US-5216183-A | Antitumor, anticarcinogenic agents; bone formation accelerators | TEIJIN LIMITED (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |