Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546184 | 0.86 | EPHX2 (0.42) | ALOX5EPHX2OXER1CNR2PDE4D | |
| SCHEMBL9546183 | 0.86 | EPHX2 (0.42) | ALOX5EPHX2OXER1CNR2PDE4D | |
| SCHEMBL9546431 | 0.81 | PDE4D (0.37) | ALOX5EPHX2PDE4DPRKCAALDH1A1 | |
| SCHEMBL9546146 | 0.81 | EPHX2 (0.41) | ALOX5EPHX2OXER1CNR2PDE4D | |
| SCHEMBL9546144 | 0.81 | EPHX2 (0.41) | ALOX5EPHX2OXER1CNR2PDE4D | |
| SCHEMBL9546080 | 0.79 | EPHX2 (0.46) | ALOX5EPHX2OXER1CNR2CNR1 | |
| SCHEMBL9546075 | 0.79 | EPHX2 (0.46) | ALOX5EPHX2OXER1CNR2CNR1 | |
| SCHEMBL10712453 | 0.77 | EPHX2 (0.45) | ALOX5EPHX2OXER1CNR2CNR1 | |
| SCHEMBL10607071 | 0.75 | EPHX2 (0.44) | ALOX5EPHX2OXER1CNR2CNR1 | |
| SCHEMBL10607027 | 0.75 | EPHX2 (0.44) | ALOX5EPHX2OXER1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |