Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.34 |
| ▸ | FPR2 | P25090 | 4/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734633 | 0.86 | PTGER3 (0.35) | PPARGPTGER3PTGER4PDE4DKDM4E | |
| SCHEMBL11406810 | 0.82 | PDE4D (0.39) | PTGER3PTGER4PDE4DKDM4EALDH1A1 | |
| SCHEMBL11040496 | 0.82 | PDE4D (0.39) | PTGER3PTGER4PDE4DKDM4EALDH1A1 | |
| SCHEMBL10620207 | 0.82 | PDE4D (0.39) | PTGER3PTGER4PDE4DKDM4EALDH1A1 | |
| SCHEMBL11039586 | 0.82 | PDE4D (0.39) | PTGER3PTGER4PDE4DKDM4EALDH1A1 | |
| SCHEMBL11039587 | 0.82 | PDE4D (0.39) | PTGER3PTGER4PDE4DKDM4EALDH1A1 | |
| SCHEMBL11400142 | 0.82 | PDE4D (0.39) | PTGER3PTGER4PDE4DKDM4EALDH1A1 | |
| SCHEMBL9546451 | 0.81 | TRPA1 (0.45) | PPARGPTGER3PTGER4PDE4DKDM4E | |
| SCHEMBL9546100 | 0.78 | TRPA1 (0.34) | PPARGPTGER3PTGER4PDE4DKDM4E | |
| SCHEMBL9546377 | 0.78 | PTGER3 (0.33) | PPARGPTGER3PTGER4PDE4DKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216183-A | Antitumor, anticarcinogenic agents; bone formation accelerators | TEIJIN LIMITED (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |