Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546323 | 1.00 | TRPA1 (0.43) | TRPA1NR4A2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL9546392 | 0.89 | TRPA1 (0.55) | TRPA1NR4A2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL9546388 | 0.89 | TRPA1 (0.55) | TRPA1NR4A2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL9546100 | 0.87 | TRPA1 (0.34) | TRPA1NR4A2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL9546326 | 0.84 | TRPA1 (0.43) | TRPA1NR4A2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL9546335 | 0.84 | TRPA1 (0.43) | TRPA1NR4A2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL9546331 | 0.84 | TRPA1 (0.43) | TRPA1NR4A2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL9546329 | 0.84 | TRPA1 (0.43) | TRPA1NR4A2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL9546188 | 0.83 | TRPA1 (0.41) | TRPA1NR4A2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL9546185 | 0.83 | TRPA1 (0.41) | TRPA1NR4A2PTGER4PTGER3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |