Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PTGIR | P43119 | 3/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546392 | 1.00 | TRPA1 (0.55) | TRPA1NR4A2MEN1LMNAHPGD | |
| SCHEMBL9546323 | 0.89 | TRPA1 (0.43) | TRPA1NR4A2MEN1LMNAHPGD | |
| SCHEMBL9546318 | 0.89 | TRPA1 (0.43) | TRPA1NR4A2MEN1LMNAHPGD | |
| SCHEMBL9546188 | 0.80 | TRPA1 (0.41) | TRPA1NR4A2MEN1LMNAHPGD | |
| SCHEMBL9546185 | 0.80 | TRPA1 (0.41) | TRPA1NR4A2MEN1LMNAHPGD | |
| SCHEMBL10619546 | 0.79 | TRPA1 (0.74) | TRPA1NR4A2MEN1LMNAHPGD | |
| SCHEMBL10619552 | 0.79 | TRPA1 (0.74) | TRPA1NR4A2MEN1LMNAHPGD | |
| SCHEMBL9546100 | 0.77 | TRPA1 (0.34) | TRPA1NR4A2ALDH1A1PTGER4PTGER3 | |
| SCHEMBL9546257 | 0.76 | NR4A2 (0.48) | TRPA1NR4A2MEN1HPGDKMT2A | |
| SCHEMBL9546254 | 0.76 | NR4A2 (0.48) | TRPA1NR4A2MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |