Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.51 |
| ▸ | CPB1 | P15086 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29816675 | 0.92 | HTR2C (0.52) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL10614925 | 0.92 | HTR2C (0.52) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL10614922 | 0.92 | HTR2C (0.52) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL6625918 | 0.91 | FKBP1A (0.52) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL28782106 | 0.89 | HTR2C (0.49) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL29816690 | 0.88 | HTR2C (0.48) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL29816802 | 0.88 | HTR2C (0.48) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL29816886 | 0.88 | HTR2C (0.48) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL20296331 | 0.87 | HTR2C (0.56) | HTR2CSMN1; SMN2NPC1RAB9AFKBP1A | |
| SCHEMBL18410317 | 0.87 | HTR2C (0.56) | HTR2CSMN1; SMN2NPC1RAB9AFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023404-A1 | COMPOUNDS THAT MODULATE ENDOTHELIN ACTIVITY | IMMUNOPHARMACEUTICS, INC. (US) | 1993-11-25 | — | — | WO | disclosed |