Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546447 | 0.92 | HTR2C (0.57) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL10614925 | 0.87 | HTR2C (0.52) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL10614922 | 0.87 | HTR2C (0.52) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL7950324 | 0.87 | HTR2C (0.54) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL5181381 | 0.86 | HTR2C (0.49) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL28782106 | 0.84 | HTR2C (0.49) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL6625918 | 0.84 | FKBP1A (0.52) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL29816886 | 0.83 | HTR2C (0.48) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL29816690 | 0.83 | HTR2C (0.48) | HTR2CSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL29816802 | 0.83 | HTR2C (0.48) | HTR2CSMN1; SMN2NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681862-B1 | BETA-HYDROXY HETEROCYCLIC AMINES AND THEIR USE IN THE TREATMENT OF HYPERGLYCAEMIA | ATROGI AB (SE) | 2023-11-08 | — | — | EP | disclosed |
| US-11427539-B2 | Beta-hydroxy heterocyclic amines and their use in the treatment of hyperglycaemia | ATROGI AB (SE) | 2022-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11427539-B2 | Beta-hydroxy heterocyclic amines and their use in the treatment of hyperglycaemia | SLC5A1, GPR119, SLC5A2 | HTR2C 298/4885SMN1; SMN2 1660/4885NPC1 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.