Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576318 | 0.81 | HCAR2 (0.37) | TP53TSHR | |
| SCHEMBL3416380 | 0.79 | THRB (0.38) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL4566184 | 0.78 | TSHR (0.38) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL29134499 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL7652425 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL9546220 | 0.75 | ALDH1A1 (0.32) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL10912883 | 0.73 | ALDH1A1 (0.38) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL3666505 | 0.72 | TSHR (0.38) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL41967 | 0.72 | ALDH1A1 (0.36) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL221767 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023773-A1 | PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL | CIBA-GEIGY AG (CH) | 1993-11-25 | — | — | WO | disclosed |