Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 8/20 | 0.42 |
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546537 | 0.90 | PSEN1 (0.44) | CCR5RENP2RX7 | |
| SCHEMBL9546814 | 0.89 | CCR5 (0.39) | CCR5UBE2MDCUN1D1CCR1REN | |
| SCHEMBL9546818 | 0.89 | CCR5 (0.39) | CCR5UBE2MDCUN1D1CCR1REN | |
| SCHEMBL9546622 | 0.83 | PSEN1 (0.49) | CCR5CCR1REN | |
| SCHEMBL9546605 | 0.83 | PSEN1 (0.49) | CCR5CCR1REN | |
| SCHEMBL9546613 | 0.83 | PSEN1 (0.49) | CCR5CCR1REN | |
| SCHEMBL9546598 | 0.83 | PSEN1 (0.49) | CCR5CCR1REN | |
| SCHEMBL9546695 | 0.77 | OPRD1 (0.39) | CCR1REN | |
| SCHEMBL9546674 | 0.77 | OPRD1 (0.39) | CCR1REN | |
| SCHEMBL9546684 | 0.77 | OPRD1 (0.39) | CCR1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023373-A1 | N-[N'-(5-AMINO-4-HYDROXY-ACYLOYL)-α-AMINOACYLOYL] SUBSTITUTED HETEROCYCLES AND THEIR USE AS ANTIVIRAL AGENTS | PFIZER LIMITED (GB) | 1993-11-25 | — | — | WO | disclosed |