Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409289 | 0.89 | HPGD (0.55) | HPGDCNR2TRPV1CNR1HDAC6 | |
| SCHEMBL513770 | 0.76 | HPGD (0.57) | HPGDABCG2NPC1RAB9APKM | |
| SCHEMBL512253 | 0.74 | HPGD (0.63) | HPGDABCG2NPC1RAB9APKM | |
| SCHEMBL18320656 | 0.73 | HPGD (0.54) | HPGDDAGLAABCG2NPC1RAB9A | |
| SCHEMBL4407303 | 0.73 | HPGD (0.57) | HPGDABCG2NPC1RAB9APKM | |
| SCHEMBL5739285 | 0.72 | HPGD (0.49) | HPGDHDAC6ABCG2NPC1RAB9A | |
| SCHEMBL4409279 | 0.70 | HPGD (0.54) | HPGDDAGLAABCG2NPC1RAB9A | |
| SCHEMBL4406572 | 0.70 | ABCG2 (0.50) | HPGDABCG2NPC1RAB9APKM | |
| SCHEMBL3229757 | 0.70 | HPGD (0.50) | HPGDDAGLAABCG2SIGMAR1 | |
| SCHEMBL9077369 | 0.70 | CNR2 (0.38) | CNR2TRPV1CNR1HDAC6MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023373-A1 | N-[N'-(5-AMINO-4-HYDROXY-ACYLOYL)-α-AMINOACYLOYL] SUBSTITUTED HETEROCYCLES AND THEIR USE AS ANTIVIRAL AGENTS | PFIZER LIMITED (GB) | 1993-11-25 | — | — | WO | disclosed |