Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9278909 | 0.80 | KDM4E (0.43) | KDM4EMEN1KMT2AGAALMNA | |
| SCHEMBL9844934 | 0.79 | KDM4E (0.44) | KDM4EMEN1KMT2AGAALMNA | |
| SCHEMBL5687930 | 0.76 | PDE4A (0.47) | LMNAALDH1A1NPSR1PDE4AADORA2A | |
| SCHEMBL10858163 | 0.75 | ALDH1A1 (0.43) | KDM4EMEN1KMT2AGAALMNA | |
| SCHEMBL1061386 | 0.72 | ALDH1A1 (0.51) | LMNAALDH1A1NPSR1PDE4AADORA2A | |
| SCHEMBL13746372 | 0.71 | PDE4A (0.43) | LMNAALDH1A1NPSR1PDE4AADORA2A | |
| Hydrochloric Acid SCHEMBL1565880 | 0.71 | ALDH1A1 (0.50) | LMNAALDH1A1NPSR1PDE4AADORA2A | |
| SCHEMBL18833894 | 0.71 | KDM4E (0.46) | KDM4EMEN1KMT2AGAALMNA | |
| SCHEMBL4251917 | 0.69 | PDE4A (0.46) | KDM4EGAALMNAALDH1A1NPSR1 | |
| SCHEMBL5996030 | 0.67 | GRIN2D (0.58) | KDM4EMEN1KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021949-A1 | IMMUNOLOGICAL DETECTION AND QUANTIFICATION OF 8-(CYCLOALKYL OR AROMATIC) SUBSTITUTED-1,3-DIPROPYLXANTHINES | VANDERBILT UNIVERSITY (US) | 1993-11-11 | — | — | WO | disclosed |