Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TRPC5 | Q9UL62 | 4/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834573 | 0.76 | TRPC5 (0.51) | ALDH1A1TRPC5TP53 | |
| SCHEMBL9844934 | 0.75 | KDM4E (0.44) | KDM4ELMNAGAAMEN1KMT2A | |
| SCHEMBL18835106 | 0.73 | ALDH1A1 (0.37) | KDM4ELMNAPDE4APDE4BPDE4C | |
| SCHEMBL9546987 | 0.71 | KDM4E (0.57) | KDM4ELMNAPDE4APDE4BPDE4C | |
| SCHEMBL18834990 | 0.68 | ALDH1A1 (0.48) | LMNAMEN1KMT2AALDH1A1TRPC5 | |
| SCHEMBL19969556 | 0.67 | ALDH1A1 (0.46) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL13814943 | 0.65 | ALDH1A1 (0.47) | KDM4ELMNAGAAMEN1KMT2A | |
| SCHEMBL1546765 | 0.63 | PDE4A (0.46) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9844929 | 0.63 | ALDH1A1 (0.51) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL10151084 | 0.63 | ALDH1A1 (0.42) | KDM4ELMNAGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |