SCHEMBL9547170

SCHEMBL9547170

[CH2]N(CCOC(=O)OCC=C)C(=O)OCC=C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.32
MAPT P10636 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9547177 0.81 CHRNB2 (0.36) CYP3A4TDP1TSHRMAPTCACNA1B
SCHEMBL176184 0.78 CYP3A4 (0.43) CYP3A4TDP1TSHRMAPTCACNA1B
Ethylene SCHEMBL167446 0.76 CYP3A4 (0.42) CYP3A4TDP1TSHRMAPTCACNA1B
SCHEMBL9928 0.76 CYP3A4 (0.48) CYP3A4TDP1TSHRMAPTCACNA1B
SCHEMBL17865874 0.75 CYP3A4 (0.38) CYP3A4TDP1TSHRMAPTCACNA1B
SCHEMBL9547288 0.74 ZDHHC20 (0.39) MAPTCACNA1BAPBA1
SCHEMBL2023648 0.74 TSHR (0.48) CYP3A4TDP1TSHRMAPTCACNA1B
SCHEMBL188677 0.74 TSHR (0.43) CYP3A4TDP1TSHRMAPTCACNA1B
SCHEMBL14313839 0.74 TSHR (0.53) CYP3A4TDP1TSHR
SCHEMBL4194213 0.74 TDP1 (0.35) CYP3A4TDP1TSHRMAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993023402-A1 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-11-25 WO claimed
WO-1993023402-A1 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-11-25 WO disclosed