Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547251 | 0.79 | MAPT (0.40) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL9547290 | 0.78 | MAPT (0.39) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL17865874 | 0.78 | CYP3A4 (0.38) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL9547084 | 0.73 | DPP4 (0.38) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL2070387 | 0.73 | MAPT (0.42) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL9547338 | 0.71 | — | — | |
| SCHEMBL12006510 | 0.71 | — | — | |
| SCHEMBL9482612 | 0.71 | CYP3A4 (0.39) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL9547170 | 0.70 | CYP3A4 (0.33) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL3673218 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084173-A | 1-azabicyclo [3,2,0] hept-2-ene\"-2-carboxylic acid derivative and preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-03-23 | — | — | CN | claimed |
| CN-1084173-A | 1-azabicyclo [3,2,0] hept-2-ene\"-2-carboxylic acid derivative and preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-03-23 | — | — | CN | disclosed |
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |