Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547259 | 0.85 | MAPT (0.36) | MAPTCACNA1BAPBA1 | |
| SCHEMBL9547291 | 0.81 | ZDHHC20 (0.40) | DPP4MAPTZDHHC20ZDHHC2TSHR | |
| SCHEMBL9547290 | 0.80 | MAPT (0.39) | MAPTCACNA1BAPBA1TSHRCYP3A4 | |
| SCHEMBL9547277 | 0.79 | ZDHHC20 (0.38) | DPP4MAPTCACNA1BAPBA1ZDHHC20 | |
| SCHEMBL9547288 | 0.76 | ZDHHC20 (0.39) | DPP4MAPTCACNA1BAPBA1ZDHHC20 | |
| SCHEMBL21445851 | 0.73 | DPP4 (0.39) | DPP4MAPTCACNA1BAPBA1ZDHHC20 | |
| SCHEMBL9547244 | 0.73 | MAPT (0.41) | MAPTCACNA1BAPBA1TSHRCYP3A4 | |
| SCHEMBL9482612 | 0.72 | CYP3A4 (0.39) | MAPTCACNA1BAPBA1TSHRCYP3A4 | |
| SCHEMBL9547251 | 0.71 | MAPT (0.40) | MAPTCACNA1BAPBA1TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL9547367 | 0.71 | MAPT (0.32) | MAPTCACNA1BAPBA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |