Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 11/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547266 | 0.77 | KDM1A (0.44) | KDM1AMEN1KMT2AGAAPOLB | |
| SCHEMBL9547241 | 0.70 | TOP2A (0.51) | KDM1AMEN1KMT2AGAAPOLB | |
| SCHEMBL9547296 | 0.68 | MEN1 (0.39) | KDM1AMEN1KMT2AGAAPOLB | |
| SCHEMBL5404455 | 0.65 | KMT2A (0.48) | KDM1AMEN1KMT2AGAAPOLB | |
| SCHEMBL9547253 | 0.65 | KDM1A (0.42) | KDM1AMEN1KMT2AGAAPOLB | |
| SCHEMBL4939495 | 0.63 | MEN1 (0.67) | KDM1AMEN1KMT2AGAAPOLB | |
| SCHEMBL4658830 | 0.62 | KDM1A (0.67) | KDM1AMEN1KMT2AGAAPOLB | |
| SCHEMBL23630584 | 0.62 | KDM1A (0.78) | KDM1AMEN1KMT2AGAAPOLB | |
| SCHEMBL14116117 | 0.61 | KMT2A (0.97) | KDM1AMEN1KMT2AGAAPOLB | |
| SCHEMBL4939506 | 0.60 | KDM1A (0.75) | KDM1AMEN1KMT2AGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023049-A1 | 3-(9-ACRIDINYLAMINO)-5-HYDROXYMETHYLANILINE DERIVATIVES AS ANTICANCER AGENTS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1993-11-25 | — | — | WO | claimed |