Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547333 | 1.00 | CYP11B1 (0.39) | CYP11B1CYP11B2ENPP2SIRT2HDAC3 | |
| SCHEMBL26704592 | 0.80 | KDM4E (0.44) | CYP11B1CYP11B2ENPP2HDAC6MEN1 | |
| SCHEMBL4022652 | 0.78 | CYP11B1 (0.43) | CYP11B1CYP11B2ENPP2SIRT2MEN1 | |
| SCHEMBL312750 | 0.78 | CYP11B1 (0.43) | CYP11B1CYP11B2ENPP2SIRT2MEN1 | |
| SCHEMBL7684568 | 0.77 | CYP11B1 (0.40) | CYP11B1CYP11B2ENPP2SIRT2MEN1 | |
| SCHEMBL7684566 | 0.77 | CYP11B1 (0.40) | CYP11B1CYP11B2ENPP2SIRT2MEN1 | |
| SCHEMBL8687555 | 0.76 | CYP11B1 (0.42) | CYP11B1CYP11B2ENPP2SIRT2MEN1 | |
| SCHEMBL6714982 | 0.76 | RAB9A (0.42) | CYP11B1CYP11B2ENPP2SIRT2HDAC3 | |
| SCHEMBL4386360 | 0.76 | CYP11B1 (0.39) | CYP11B1CYP11B2ENPP2SIRT2CYP3A4 | |
| SCHEMBL6923215 | 0.76 | CYP11B1 (0.42) | CYP11B1CYP11B2ENPP2SIRT2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |